LITERATURE REVIEW : OVERVIEW OF MEAN PLATELET VOLUME AND COUNT PLATELET IN PATIENTS WITH DIABETES MELLITUS TIPE II

Abstract

a deficiency of insulin secretion. Type II Diabetes Mellitus is characterized by decreased insulin sensitivity. In type II diabetes mellitus, there is an acceleration of thrombopoiesis and an increase in platelet turnover.  This study aims to determine the description of MPV (Mean Platelet Volume) and platelet count in patients with type II Diabetes Mellitus. Methodology : The research design used is the Literature Review method . Data collection uses electronic databases, namely Google Scholar, Pubmed and Researchgate, both national and international journals. Research findings : Data collection was carried out through 3 analyzed journals. Where in the three journals analyzed, the results of the platelet count varied, while the MPV increased in patients with type II diabetes mellitus. Conclusions : Based on the results of a literature review that has been carried out by researchers, it can be concluded that there are variations in the description of the platelet count in type II diabetes mellitus, there is a decrease in the platelet count and the result in the platelet count in the normal range (254,550-284,210 cells/mm3). However, the value of MPV increased in patients with type II diabetes mellitus in the range (7.4 – 9.91 fL).